Structure of PDB 1nki Chain B

Receptor sequence
>1nkiB (length=134) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
MLTGLNHLTLAVADLPASIAFYRDLLGFRLEARWDQGAYLELGSLWLCLS
REPQYGGPAADYTHYAFGIAAADFARFAAQLRAHGVREWKQNRSEGDSFY
FLDPDGHRLEAHVGDLRSRLAACRQAPYAGMRFA
3D structure
PDB1nki Phosphonoformate: a minimal transition state analogue inhibitor of the fosfomycin resistance protein, FosA.
ChainB
Resolution0.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B H64 E110 H64 E110
BS02 PPF B Y62 H64 S94 Y100 E110 R119 Y62 H64 S94 Y100 E110 R119 MOAD: Kd=0.2uM
PDBbind-CN: -logKd/Ki=6.70,Kd=0.2uM
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0046677 response to antibiotic
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:1nki, PDBe:1nki, PDBj:1nki
PDBsum1nki
PubMed15504029
UniProtQ9I4K6|FOSA_PSEAE Glutathione transferase FosA (Gene Name=fosA)

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