Structure of PDB 1njt Chain B

Receptor sequence
>1njtB (length=227) Species: 10359 (Human betaherpesvirus 5) [Search protein sequence]
TMDEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQALPLN
INHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRG
PVSPLQPDKVVEFLSGSYAGLSLSSRRCDTTPFKHVALCSVGRRRGTLAV
YGRDPEWVTQRFPDLTAADRDGLRAQWQRCSGDPFRSDSYGLLGNSVDAL
YIRERLPKLRYDKQLVGVTERESYVKA
3D structure
PDB1njt Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease
ChainB
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H363 S432 S434 H457 R465 R466
Catalytic site (residue number reindexed from 1) H53 S122 S124 H135 R143 R144
Enzyme Commision number 3.4.21.97: assemblin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B H363 S432 L433 S434 S435 R436 R437 K456 G464 R465 H53 S122 L123 S124 S125 R126 R127 K134 G142 R143
BS02 peptide B H363 S432 R465 H53 S122 R143
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1njt, PDBe:1njt, PDBj:1njt
PDBsum1njt
PubMed12549906
UniProtP16753|SCAF_HCMVA Capsid scaffolding protein (Gene Name=UL80)

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