Structure of PDB 1n2x Chain B

Receptor sequence
>1n2xB (length=278) Species: 2336 (Thermotoga maritima) [Search protein sequence]
HIPVMVREVIEFLKPEDEKIILDCTVGEGGHSRAILEHCPGCRIIGIDVD
SEVLRIAEEKLKEFSDRVSLFKVSYREADFLLKTLGIEKVDGILMDLGVS
TYQLKGENRGFTFEREEPLDMRMDLESEVTAQKVLNELPEEELARIIFEY
GEEKRFARRIARKIVENRPLNTTLDLVKAVREALPSYEIRRRKRHFATKT
FQAIRIYVNRELENLKEFLKKAEDLLNPGGRIVVISFHSLEDRIVKETFR
NSKKLRILTEKPVRPSPRARSGRLRAAE
3D structure
PDB1n2x Crystal complexes of a predicted S-adenosylmethionine-dependent methyltransferase reveal a typical AdoMet binding domain and a substrate recognition domain
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.199: 16S rRNA (cytosine(1402)-N(4))-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM B H8 T32 V33 G34 E35 G37 H38 D55 V56 S81 Y82 D103 G105 V106 Q110 H1 T25 V26 G27 E28 G30 H31 D48 V49 S74 Y75 D96 G98 V99 Q103
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0071424 rRNA (cytosine-N4-)-methyltransferase activity
Biological Process
GO:0006364 rRNA processing
GO:0032259 methylation
GO:0070475 rRNA base methylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1n2x, PDBe:1n2x, PDBj:1n2x
PDBsum1n2x
PubMed12824489
UniProtQ9WZX6|RSMH_THEMA Ribosomal RNA small subunit methyltransferase H (Gene Name=rsmH)

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