Structure of PDB 1n23 Chain B

Receptor sequence
>1n23B (length=527) Species: 38868 (Salvia officinalis) [Search protein sequence]
QPALWDSNYIQSLNTPYTEERHLDRKAELIVQVRILLKEKMEPVQQLELI
HDLKYLGLSDFFQDEIKEILGVIYNEHKCDLYFTALGFRLLRQHGFNISQ
DVFNCFKNEKGIDFKASLAQDTKGMLQLYEASFLLRKGEDTLELAREFAT
KCLQKKLDENEIDENLLLWIRHSLDLPLHWRIQSVEARWFIDAYARRPDM
NPLIFELAKLNFNIIQATHQQELKDLSRWWSRLCFPEKLPFVRDRLVESF
FWAVGMFEPHQHGYQRKMAATIIVLATVIDDIYDVYGTLDELELFTDTFK
RWDTESITRLPYYMQLCYWGVHNYISDAAYDILKEHGFFCLQYLRKSVVD
LVEAYFHEAKWYHSGYTPSLDEYLNIAKISVASPAIISPTYFTFANASHD
TAVIDSLYQYHDILCLAGIILRLPDDLGTSYFELARGDVPKTIQCYMKET
NASEEEAVEHVKFLIREAWKDMNTAIAAGYPFPDGMVAGAANIGRVAQFI
YLHGDGFGVQHSKTYEHIAGLLFEPYA
3D structure
PDB1n23 Bornyl diphosphate synthase: Structure and strategy for carbocation manipulation by a terpenoid cyclase
ChainB
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) R314 W323 I344 D351 D355 S451 V452 A453 R493 D496 T500 E504 Y572 D576 F578
Catalytic site (residue number reindexed from 1) R243 W252 I273 D280 D284 S380 V381 A382 R422 D425 T429 E433 Y501 D505 F507
Enzyme Commision number 4.2.3.116: (+)-camphene synthase.
4.2.3.121: (+)-alpha-pinene synthase.
5.5.1.8: (+)-bornyl diphosphate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B D351 D355 D280 D284
BS02 MG B D351 D355 D280 D284
BS03 MG B D496 T500 E504 D425 T429 E433
BS04 2BN B T348 V452 F578 T277 V381 F507
BS05 POP B R314 D351 R493 D496 E504 R243 D280 R422 D425 E433
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0010333 terpene synthase activity
GO:0016829 lyase activity
GO:0016853 isomerase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0047926 geranyl-diphosphate cyclase activity
GO:0050550 pinene synthase activity
GO:0102703 camphene synthase activity
Biological Process
GO:0016102 diterpenoid biosynthetic process
GO:0016114 terpenoid biosynthetic process
GO:0046211 (+)-camphor biosynthetic process
Cellular Component
GO:0009507 chloroplast

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1n23, PDBe:1n23, PDBj:1n23
PDBsum1n23
PubMed12432096
UniProtO81192|BPPS_SALOF (+)-bornyl diphosphate synthase, chloroplastic

[Back to BioLiP]