Structure of PDB 1mzo Chain B

Receptor sequence
>1mzoB (length=756) Species: 562 (Escherichia coli) [Search protein sequence]
NEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTL
WDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEA
PLKRALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYT
PDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSL
QADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQE
AIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQE
MVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNS
FRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDD
LMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEK
LKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDK
YSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGL
AIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSV
LTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAK
LPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQ
HLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITR
TFTQSM
3D structure
PDB1mzo Structure of Escherichia coli pyruvate formate-lyase with pyruvate.
ChainB
Resolution2.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) W333 C418 C419 G734
Catalytic site (residue number reindexed from 1) W330 C415 C416 G731
Enzyme Commision number 2.3.1.54: formate C-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PYR B R176 W333 C418 F432 R435 I606 R173 W330 C415 F429 R432 I603
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0008861 formate C-acetyltransferase activity
GO:0016746 acyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006006 glucose metabolic process
GO:0044814 glycolytic fermentation via PFL pathway
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1mzo, PDBe:1mzo, PDBj:1mzo
PDBsum1mzo
PubMed12454503
UniProtP09373|PFLB_ECOLI Formate acetyltransferase 1 (Gene Name=pflB)

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