Structure of PDB 1mp3 Chain B

Receptor sequence
>1mp3B (length=289) Species: 28901 (Salmonella enterica) [Search protein sequence]
MKTRKGIILAGGSGTRLYPVTMAVSQQLLPIYDKPMIYYPLSTLMLAGIR
DILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGTAQAFIIGEEFI
GHDDCALVLGDNIFYGHDLPKLMEAAVNKESGATVFAYHVNDPERYGVVE
FDQAGTAVSLEEKPLQPKSNYAVTGLYFYDNSVVEMAKNLKPSARGELEI
TDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATIEERQGLK
VSCPEEIAFRKNFINAQQVIELAGPLSKNDYGKYLLKMV
3D structure
PDB1mp3 Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
ChainB
Resolution2.2 Å
3D
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Enzymatic activity
Enzyme Commision number 2.7.7.24: glucose-1-phosphate thymidylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TTP B G219 R220 G221 G219 R220 G221
BS02 TTP B Y115 G116 H117 S252 E256 I257 Y115 G116 H117 S252 E256 I257
BS03 TTP B L9 G11 G12 G14 T15 R16 Q27 Q83 P86 G88 D111 L9 G11 G12 G14 T15 R16 Q27 Q83 P86 G88 D111
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008879 glucose-1-phosphate thymidylyltransferase activity
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0009058 biosynthetic process
GO:0045226 extracellular polysaccharide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1mp3, PDBe:1mp3, PDBj:1mp3
PDBsum1mp3
PubMed12374866
UniProtQ9F7G8

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