Structure of PDB 1m8p Chain B

Receptor sequence
>1m8pB (length=573) Species: 5076 (Penicillium chrysogenum) [Search protein sequence]
MANAPHGGVLKDLLARDAPRQAELAAEAESLPAVTLTERQLCDLELIMNG
GFSPLEGFMNQADYDRVCEDNRLADGNVFSMPITLDASQEVIDEKKLQAA
SRITLRDFRDDRNLAILTIDDIYRPDKTKEAKLVFGGDPEHPAIVYLNNT
VKEFYIGGKIEAVNKLNHYDYVALRYTPAELRVHFDKLGWSRVVAFQTRN
PMHRAHRELTVRAARSRQANVLIHPVVGLTKPGDIDHFTRVRAYQALLPR
YPNGMAVLGLLGLAMRMGGPREAIWHAIIRKNHGATHFIVGRDHAGPGSN
SKGEDFYGPYDAQHAVEKYKDELGIEVVEFQMVTYLPDTDEYRPVDQVPA
GVKTLNISGTELRRRLRSGAHIPEWFSYPEVVKILRESNPPRATQGFTIF
LTGYMNSGKDAIARALQVTLNQQGGRSVSLLLGDTVRHELSSELGFTRED
RHTNIQRIAFVATELTRAGAAVIAAPIAPYEESRKFARDAVSQAGSFFLV
HVATPLEHCEQSDKRGIYAAARRGEIKGFTGVDDPYETPEKADLVVDFSK
QSVRSIVHEIILVLESQGFLERQ
3D structure
PDB1m8p Allosteric Inhibition via R-State Destabilization in ATP Sulfurylase from Penicillium chrysogenum
ChainB
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T198 R199 H203 H206 R292
Catalytic site (residue number reindexed from 1) T198 R199 H203 H206 R292
Enzyme Commision number 2.7.7.4: sulfate adenylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PPS B M405 R437 F446 R451 N454 P476 I477 A478 P479 R515 G528 F529 T530 M405 R437 F446 R451 N454 P476 I477 A478 P479 R515 G528 F529 T530
Gene Ontology
Molecular Function
GO:0004020 adenylylsulfate kinase activity
GO:0004781 sulfate adenylyltransferase (ATP) activity
GO:0005524 ATP binding
Biological Process
GO:0000103 sulfate assimilation

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Molecular Function
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Biological Process
External links
PDB RCSB:1m8p, PDBe:1m8p, PDBj:1m8p
PDBsum1m8p
PubMed12426581
UniProtQ12650|MET3_PENCH Sulfate adenylyltransferase (Gene Name=met3)

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