Structure of PDB 1m72 Chain B

Receptor sequence
>1m72B (length=248) Species: 7108 (Spodoptera frugiperda) [Search protein sequence]
VARMPVDRNAPYYNMNHKHRGMAIIFNHEHFDIHSLKSRTGTNVDSDNLS
KVLKTLGFKVTVFPNLKSEEINKFIQQTAEMDHSDADCLLVAVLTHGELG
MLYAKDTHYKPDNLWYYFTADKCPTLAGKPKLFFIQACQGDRLDGGITLS
RTSYRIPVHADFLIAFSTVPGYFSWRNTTRGSWFMQALCEELRYAGTERD
ILTLLTFVCQKVALDFESNAPDSAMMHQQKQVPCITSMLTRLLVFGKK
3D structure
PDB1m72 Crystal structure of an invertebrate caspase.
ChainB
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K77 S78 G137 C178
Catalytic site (residue number reindexed from 1) K37 S38 G97 C138
Enzyme Commision number 3.4.22.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R79 H136 C178 F221 S222 W223 R224 N225 T226 S266 N267 R39 H96 C138 F173 S174 W175 R176 N177 T178 S218 N219
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Biological Process
GO:0006508 proteolysis
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0097190 apoptotic signaling pathway
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1m72, PDBe:1m72, PDBj:1m72
PDBsum1m72
PubMed14645217
UniProtP89116|CASP1_SPOFR Caspase-1

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