Structure of PDB 1m2o Chain B

Receptor sequence
>1m2oB (length=164) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
GKLLFLGLDNAGKTTLLHMLKNDRLATLQPTWHPTSEELAIGNIKFTTFD
LGGHIQARRLWKDYFPEVNGIVFLVDAADPERFDEARVELDALFNIAELK
DVPFVILGNKIDAPNAVSEAELRSALGLLNTTGIEGQRPVEVFMCSVVMR
NGYLEAFQWLSQYI
3D structure
PDB1m2o Structure of the Sec23/24-Sar1 pre-budding complex of the COPII vesicle coat
ChainB
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H77
Catalytic site (residue number reindexed from 1) H54
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B T37 T54 T14 T31
BS02 GNP B D32 N33 G35 K36 T37 T38 T54 G76 N132 K133 D135 S172 V173 V174 D9 N10 G12 K13 T14 T15 T31 G53 N109 K110 D112 S146 V147 V148
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0016787 hydrolase activity
Biological Process
GO:0000266 mitochondrial fission
GO:0003400 regulation of COPII vesicle coating
GO:0006886 intracellular protein transport
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0006998 nuclear envelope organization
GO:0007006 mitochondrial membrane organization
GO:0015031 protein transport
GO:0016050 vesicle organization
GO:0016192 vesicle-mediated transport
GO:0061024 membrane organization
GO:0070863 positive regulation of protein exit from endoplasmic reticulum
GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0012507 ER to Golgi transport vesicle membrane
GO:0016020 membrane
GO:0030127 COPII vesicle coat
GO:0031410 cytoplasmic vesicle
GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site
GO:0070971 endoplasmic reticulum exit site

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1m2o, PDBe:1m2o, PDBj:1m2o
PDBsum1m2o
PubMed12239560
UniProtP20606|SAR1_YEAST Small COPII coat GTPase SAR1 (Gene Name=SAR1)

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