Structure of PDB 1lvb Chain B

Receptor sequence
>1lvbB (length=214) Species: 12227 (Tobacco etch virus) [Search protein sequence]
PRDYNPISSTICHLTNESDGHTTSLYGIGFGPFIITNKHLFRRNNGTLLV
QSLHGVFKVKNTTTLQQHLIDGRDMIIIRMPKDFPPFPQKLKFREPQREE
RICLVTTNFQTKSMSSMVSDTSCTFPSSDGIFWKHWIQTKDGQAGSPLVS
TRDGFIVGIHSASNFTNTNNYFTSVPKNFMELLTNQEAQQWVSGWRLNAD
SVLWGGHKVFMSKP
3D structure
PDB1lvb Structural basis for the substrate specificity of tobacco etch virus protease.
ChainB
Resolution2.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.-.-
3.4.22.44: nuclear-inclusion-a endopeptidase.
3.4.22.45: helper-component proteinase.
3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B T29 T30 S31 H46 D81 T146 D148 G149 A151 H167 S168 A169 S170 N171 F172 N176 Y178 G213 H214 K215 V216 F217 M218 K220 T22 T23 S24 H39 D74 T139 D141 G142 A144 H160 S161 A162 S163 N164 F165 N169 Y171 G206 H207 K208 V209 F210 M211 K213
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1lvb, PDBe:1lvb, PDBj:1lvb
PDBsum1lvb
PubMed12377789
UniProtP04517|POLG_TEV Genome polyprotein

[Back to BioLiP]