Structure of PDB 1lfd Chain B

Receptor sequence
>1lfdB (length=167) Species: 9606 (Homo sapiens) [Search protein sequence]
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDKYDPTIEDSYRKQVVIDGET
CLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQI
KRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQ
GVEDAFYTLVREIRQHK
3D structure
PDB1lfd Structural basis for the interaction of Ras with RalGDS.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B S217 D233 T235 S17 D33 T35
BS02 GNP B G213 G215 K216 S217 A218 F228 D230 T235 G260 N316 K317 D319 S345 A346 G13 G15 K16 S17 A18 F28 D30 T35 G60 N116 K117 D119 S145 A146
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1lfd, PDBe:1lfd, PDBj:1lfd
PDBsum1lfd
PubMed9628477
UniProtP01112|RASH_HUMAN GTPase HRas (Gene Name=HRAS)

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