Structure of PDB 1lat Chain B

Receptor sequence
>1latB (length=74) Species: 10116 (Rattus norvegicus) [Search protein sequence]
ARPCLVCSDEASGCHYGVLTCEGCKAFFKRAVEGQHNYLCKYEGKCIIDK
IRRKNCPACRYRKCLQAGMNLEAR
3D structure
PDB1lat The basis for half-site specificity explored through a non-cognate steroid receptor-DNA complex.
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B E458 R466 R489 K490 P493 R496 E22 R30 R53 K54 P57 R60
BS02 dna B C450 H451 Y452 K461 K465 R510 C14 H15 Y16 K25 K29 R74
BS03 ZN B C440 C443 C457 C460 C4 C7 C21 C24
BS04 ZN B C476 C482 C492 C495 C40 C46 C56 C59
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:1lat, PDBe:1lat, PDBj:1lat
PDBsum1lat
PubMed7664096
UniProtP06536|GCR_RAT Glucocorticoid receptor (Gene Name=Nr3c1)

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