Structure of PDB 1l6o Chain B

Receptor sequence
>1l6oB (length=93) Species: 8355 (Xenopus laevis) [Search protein sequence]
MIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEP
GDMLLQVNDINFENMSNDDAVRVLRDIVHKPGPIVLTVAKLEH
3D structure
PDB1l6o Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y282 L341 E342 H343 Y32 L91 E92 H93
BS02 peptide B F264 L265 G266 I267 S268 I269 V270 G271 S273 V321 F14 L15 G16 I17 S18 I19 V20 G21 S23 V71
Gene Ontology
Biological Process
GO:0016055 Wnt signaling pathway

View graph for
Biological Process
External links
PDB RCSB:1l6o, PDBe:1l6o, PDBj:1l6o
PDBsum1l6o
PubMed11970895
UniProtP51142|DVL2_XENLA Segment polarity protein dishevelled homolog DVL-2 (Gene Name=dvl2)

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