Structure of PDB 1kny Chain B

Receptor sequence
>1knyB (length=253) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
MNGPIIMTREERMKIVHEIKERILDKYGDDVKAIGVYGSLGRQTDGPYSD
IEMMCVMSTEEAEFSHEWTTGEWKVEVNFYSEEILLDYASQVESDWPLTH
GQFFSILPIYDSGGYLEKVYQTAKSVEAQTFHDAICALIVEELFEYAGKW
RNIRVQGPTTFLPSLTVQVAMAGAMLIGLHHRICYTTSASVLTEAVKQSD
LPSGYDHLCQFVMSGQLSDSEKLLESLENFWNGIQEWTERHGYIVDVSKR
IPF
3D structure
PDB1kny Structural investigation of the antibiotic and ATP-binding sites in kanamycin nucleotidyltransferase.
ChainB
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D50 E52 E145 K149
Catalytic site (residue number reindexed from 1) D50 E52 E145 K149
Enzyme Commision number 2.7.7.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B D50 E52 D50 E52
BS02 APC B S39 R42 S49 E52 T99 T187 S39 R42 S49 E52 T99 T187
BS03 KAN B S94 D95 E141 E145 S94 D95 E141 E145
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:1kny, PDBe:1kny, PDBj:1kny
PDBsum1kny
PubMed7577914
UniProtP05057|KANU_STAAU Kanamycin nucleotidyltransferase (Gene Name=knt)

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