Structure of PDB 1kfi Chain B

Receptor sequence
>1kfiB (length=570) Species: 5888 (Paramecium tetraurelia) [Search protein sequence]
QVIPAPRVQVTQPYAGQKPGTSGLRKKVSEATQPNYLENFVQSIFNTLRK
DELKPKNVLFVGGDGRYFNRQAIFSIIRLAYANDISEVHVGQAGLMSTPA
SSHYIRKVNEEVGNCIGGIILTASHNPGGKEHGDFGIKFNVRTGAPAPED
FTDQIYTHTTKIKEYLTVDYEFEKHINLDQIGVYKFEGTRLEKSHFEVKV
VDTVQDYTQLMQKLFDFDLLKGLFSNKDFSFRFDGMHGVAGPYAKHIFGT
LLGCSKESLLNCDPSEDFGGGHPDPNLTYAHDLVELLDIHKKKDVGTVPQ
FGAACDGDADRNMILGRQFFVTPSDSLAVIAANANLIFKNGLLGAARSMP
TSGALDKVAAKNGIKLFETPTGWKFFGNLMDAGLINLCGEESFGTGSNHI
REKDGIWAVLAWLTILAHKNKNTDHFVTVEEIVTQYWQQFGRNYYSRYDY
EQVDSAGANKMMEHLKTKFQYFEQLKQGNKADIYDYVDPVDQSVSKNQGV
RFVFGDGSRIIFRLSGTGSVGATIRIYFEQFEQQQIQHETATALANIIKL
GLEISDIAQFTGRNEPTVIT
3D structure
PDB1kfi Crystal structure analysis of the exocytosis-sensitive phosphoprotein, pp63/parafusin (phosphoglucomutase), from Paramecium reveals significant conformational variability.
ChainB
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S126 H127 D308 D310 D312 R313 K405
Catalytic site (residue number reindexed from 1) S124 H125 D306 D308 D310 R311 K403
Enzyme Commision number 5.4.2.2: phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B D308 D310 D312 D306 D308 D310
BS02 SO4 B S126 H127 D312 R313 W375 S124 H125 D310 R311 W373
BS03 SO4 B R515 R527 R513 R525
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004614 phosphoglucomutase activity
GO:0016853 isomerase activity
GO:0016868 intramolecular phosphotransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1kfi, PDBe:1kfi, PDBj:1kfi
PDBsum1kfi
PubMed11779235
UniProtP47244|PGM1_PARTE Phosphoglucomutase-1 (Gene Name=pp63-1)

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