Structure of PDB 1k2d Chain B

Receptor sequence
>1k2dB (length=185) Species: 10090 (Mus musculus) [Search protein sequence]
RHFVVQFQPFCYFTNGTQRIRYVTRYIYNREEYLRFDSDVGEYRAVTELG
RPDAEYYNKQYLERTRAELDTVCRYNYEETEVPTSLRRLEQPNVVISLSR
TEALNHHNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLIRNGDWTF
QVLVMLEMTPRRGEVYTCHVEHPSLKSPITVEWRA
3D structure
PDB1k2d Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B F11 Y26 Y30 D57 Y60 Y61 Y67 T71 E74 V78 Y81 N82 F7 Y22 Y26 D53 Y56 Y57 Y61 T65 E68 V72 Y75 N76
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
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Cellular Component
External links
PDB RCSB:1k2d, PDBe:1k2d, PDBj:1k2d
PDBsum1k2d
PubMed12150894
UniProtP06344|HB2U_MOUSE H-2 class II histocompatibility antigen, A-U beta chain

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