Structure of PDB 1jyq Chain B

Receptor sequence
>1jyqB (length=96) Species: 9606 (Homo sapiens) [Search protein sequence]
GSMAWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDV
QHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDI
3D structure
PDB1jyq Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R67 R86 S88 S90 S96 F101 Q106 H107 F108 K109 L120 W121 S141 R142 N143 R12 R31 S33 S35 S41 F46 Q51 H52 F53 K54 L65 W66 S86 R87 N88
External links
PDB RCSB:1jyq, PDBe:1jyq, PDBj:1jyq
PDBsum1jyq
PubMed11827484
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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