Structure of PDB 1jsp Chain B

Receptor sequence
>1jspB (length=121) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHMRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYF
DIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYK
FCSKLAEVFEQEIDPVMQSLG
3D structure
PDB1jsp Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation.
ChainB
ResolutionN/A
3D
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B V1115 I1122 Y1167 N1168 R1169 S1172 R1173 V1174 V39 I46 Y91 N92 R93 S96 R97 V98
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1jsp, PDBe:1jsp, PDBj:1jsp
PDBsum1jsp
PubMed14759370
UniProtQ92793|CBP_HUMAN CREB-binding protein (Gene Name=CREBBP)

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