Structure of PDB 1jm7 Chain B

Receptor sequence
>1jm7B (length=97) Species: 9606 (Homo sapiens) [Search protein sequence]
MEPDGRGAWAHSRAALDRLEKLLRCSRCTNILREPVCLGGCEHIFCSNCV
SDCIGTGCPVCYTPAWIQDLKINRQLDSMIQLCSKLRNLLHDNELSD
3D structure
PDB1jm7 Structure of a BRCA1-BARD1 heterodimeric RING-RING complex.
ChainB
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C71 C74 C46 C49
BS02 ZN B H68 C83 C86 H43 C58 C61
Gene Ontology
Molecular Function
GO:0003697 single-stranded DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0006301 postreplication repair
GO:0006513 protein monoubiquitination

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Molecular Function
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Biological Process
External links
PDB RCSB:1jm7, PDBe:1jm7, PDBj:1jm7
PDBsum1jm7
PubMed11573085
UniProtQ99728|BARD1_HUMAN BRCA1-associated RING domain protein 1 (Gene Name=BARD1)

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