Structure of PDB 1jca Chain B

Receptor sequence
>1jcaB (length=30) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB1jca Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B F1 N3 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 P28 F1 N3 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 P28
BS02 peptide B S9 V12 E13 Y16 G23 F24 F25 Y26 P28 S9 V12 E13 Y16 G23 F24 F25 Y26 P28
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1jca, PDBe:1jca, PDBj:1jca
PDBsum1jca
PubMed11779231
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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