Structure of PDB 1j7j Chain B

Receptor sequence
>1j7jB (length=164) [Search protein sequence]
HTVEVMIPEAEIKARIAELGRQITERYKDSGSEMVLVGLLRGSFMFMADL
CREVQVPHEVDFMTASRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKV
REILGLREPKSLAICTLLDKPSRREVDVPVEFVGFSIPDEFVVGYGIDYA
QRYRHLPYVGKVVL
3D structure
PDB1j7j Crystal Structure of the HPRT from Salmonella Typhimurium at 2.3 A Resolution
ChainB
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E99 D100 D103 F152 R165
Catalytic site (residue number reindexed from 1) E88 D89 D92 F141 R154
Enzyme Commision number 2.4.2.8: hypoxanthine phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B E99 D100 E88 D89
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0004422 hypoxanthine phosphoribosyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
GO:0052657 guanine phosphoribosyltransferase activity
Biological Process
GO:0006166 purine ribonucleoside salvage
GO:0006178 guanine salvage
GO:0032263 GMP salvage
GO:0032264 IMP salvage
GO:0046100 hypoxanthine metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1j7j, PDBe:1j7j, PDBj:1j7j
PDBsum1j7j
PubMed
UniProtO33799|HPRT_SALTY Hypoxanthine phosphoribosyltransferase (Gene Name=hpt)

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