Structure of PDB 1j3b Chain B

Receptor sequence
>1j3bB (length=518) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
QRLEALGIHPKKRVFWNTVSPVLVEHTLLRGEGLLAHHGPLVVDTTPYTG
RSPKDKFVVREPEVEGEIWWGEVNQPFAPEAFEALYQRVVQYLSERDLYV
QDLYAGADRRYRLAVRVVTESPWHALFARNMFILPRRFGNDDEVEAFVPG
FTVVHAPYFQAVPERDGTRSEVFVGISFQRRLVLIVGTKYAGEIKKSIFT
VMNYLMPKRGVFPMHASANVGKEGDVAVFFGLSGTGKTTLSTDPERPLIG
DDEHGWSEDGVFNFEGGCYAKVIRLSPEHEPLIYKASNQFEAILENVVVN
PESRRVQWDDDSKTENTRSSYPIAHLENVVESGVAGHPRAIFFLSADAYG
VLPPIARLSPEEAMYYFLSGYTARVPRATFSACFGAPFLPMHPGVYARML
GEKIRKHAPRVYLVNTGWTGGPYGVGYRFPLPVTRALLKAALSGALENVP
YRRDPVFGFEVPLEAPGVPQELLNPRETWADKEAYDQQARKLARLFQENF
QKYASGVAKEVAEAGPRT
3D structure
PDB1j3b Structure of ATP-dependent phosphoenolpyruvate carboxykinase from Thermus thermophilus HB8 showing the structural basis of induced fit and thermostability.
ChainB
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) R52 K197 H216 S234 K238 T239 D253 R319
Catalytic site (residue number reindexed from 1) R51 K196 H215 S233 K237 T238 D252 R318
Enzyme Commision number 4.1.1.49: phosphoenolpyruvate carboxykinase (ATP).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B R130 N131 F133 G267 R129 N130 F132 G266
Gene Ontology
Molecular Function
GO:0004611 phosphoenolpyruvate carboxykinase activity
GO:0004612 phosphoenolpyruvate carboxykinase (ATP) activity
GO:0005524 ATP binding
GO:0016831 carboxy-lyase activity
GO:0017076 purine nucleotide binding
GO:0046872 metal ion binding
Biological Process
GO:0006094 gluconeogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1j3b, PDBe:1j3b, PDBj:1j3b
PDBsum1j3b
PubMed16239727
UniProtQ5SLL5|PCKA_THET8 Phosphoenolpyruvate carboxykinase (ATP) (Gene Name=pckA)

[Back to BioLiP]