Structure of PDB 1io9 Chain B

Receptor sequence
>1io9B (length=354) Species: 2287 (Saccharolobus solfataricus) [Search protein sequence]
MYDWFSEMRKKDPVYYDGNIWQVFSYRYTKEVLNNFSKFSSDLTGYHERL
EDLRNGKIRFDIPTRYTMLTSDPPLHDELRSMSADIFSPQKLQTLETFIR
ETTRSLLDSIDPREDDIVKKLAVPLPIIVISKILGLPIEDKEKFKEWSDL
VLGKKYLELIGYVKDHLNSGTEVVSRVVNSNLSDIEKLGYIILLLIAGNE
TTTNLISNSVIDFTRFNLWQRIREENLYLKAIEEALRYSPPVMRTVRKTK
ERVKLGDQTIEEGEYVRVWIASANRDEEVFHDGEKFIPDRNPNPHLSFGS
GIHLCLGAPLARLEARIAIEEFSKRFRHIEILDTEKVPNEVLNGYKRLVV
RLKS
3D structure
PDB1io9 Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties.
ChainB
Resolution2.05 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A709 E712 T713 T714 C817 L818 G819 E826 L854
Catalytic site (residue number reindexed from 1) A197 E200 T201 T202 C305 L306 G307 E314 L342
Enzyme Commision number 1.11.1.7: peroxidase.
1.14.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM B L569 H576 R580 A709 G710 T713 P753 T757 R759 S809 F810 H815 C817 L818 G819 L69 H76 R80 A197 G198 T201 P241 T245 R247 S297 F298 H303 C305 L306 G307
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0004601 peroxidase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0140825 lactoperoxidase activity
Biological Process
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:1io9, PDBe:1io9, PDBj:1io9
PDBsum1io9
PubMed12237217
UniProtQ55080|CP119_SULAC Cytochrome P450 119 (Gene Name=cyp119)

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