Structure of PDB 1ice Chain B

Receptor sequence
>1iceB (length=88) Species: 9606 (Homo sapiens) [Search protein sequence]
AIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDV
EEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH
3D structure
PDB1ice Structure and mechanism of interleukin-1 beta converting enzyme.
ChainB
Resolution2.6 Å
3D
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Enzymatic activity
Enzyme Commision number 3.4.22.36: caspase-1.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B V338 S339 W340 R341 H342 V22 S23 W24 R25 H26
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1ice, PDBe:1ice, PDBj:1ice
PDBsum1ice
PubMed8035875
UniProtP29466|CASP1_HUMAN Caspase-1 (Gene Name=CASP1)

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