Structure of PDB 1ia9 Chain B

Receptor sequence
>1ia9B (length=280) Species: 10090 (Mus musculus) [Search protein sequence]
TNYYYSAVERNNLMRLSQSIPFVPVPPRGEPVTVYRLEESSPSILNNSMS
SWSQLGLCAKIEFLSKEEMGGGLRRAVKVLCTWSEHDILKSGHLYIIKSF
LPEVINTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFNQMKPKSIPYSP
RFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIMLA
FSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPANLGE
DAIKNFRAKHHCNSCCRKLKLPDLKRNDYT
3D structure
PDB1ia9 Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B H1751 H1808 C1810 C1814 H203 H260 C262 C266
BS02 ANP B G1618 G1620 L1621 R1622 A1624 K1646 C1720 M1721 F1725 D1775 G70 G72 L73 R74 A76 K98 C172 M173 F177 D227
Gene Ontology
Molecular Function
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:1ia9, PDBe:1ia9, PDBj:1ia9
PDBsum1ia9
PubMed11389851
UniProtQ923J1|TRPM7_MOUSE Transient receptor potential cation channel subfamily M member 7 (Gene Name=Trpm7)

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