Structure of PDB 1i8k Chain B

Receptor sequence
>1i8kB (length=119) Species: 10090 (Mus musculus) [Search protein sequence]
QVKLQQSGGGLVKPGASLKLSCVTSGFTFRKFGMSWVRQTSDKCLEWVAS
ISTGGYNTYYSDNVKGRFTISRENAKNTLYLQMSSLKSEDTALYYCTRGY
SSTSYAMDYWGQGTTVTVS
3D structure
PDB1i8k Antibody recognition of a conformational epitope in a peptide antigen: Fv-peptide complex of an antibody fragment specific for the mutant EGF receptor, EGFRvIII.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B S352 T353 G354 Y356 N357 Y359 S402 T403 S404 Y405 S52 T53 G54 Y56 N57 Y59 S102 T103 S104 Y105
Gene Ontology
Molecular Function
GO:0003823 antigen binding
Biological Process
GO:0002250 adaptive immune response
GO:0016064 immunoglobulin mediated immune response
Cellular Component
GO:0019814 immunoglobulin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1i8k, PDBe:1i8k, PDBj:1i8k
PDBsum1i8k
PubMed11352579
UniProtP18529|HVM58_MOUSE Ig heavy chain V region 5-76

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