Structure of PDB 1i51 Chain B

Receptor sequence
>1i51B (length=92) Species: 9606 (Homo sapiens) [Search protein sequence]
KIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQI
LTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
3D structure
PDB1i51 Structural basis of caspase-7 inhibition by XIAP.
ChainB
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.60: caspase-7.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y230 W232 R233 S234 P235 G236 S275 Q276 F282 Y19 W21 R22 S23 P24 G25 S64 Q65 F71
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1i51, PDBe:1i51, PDBj:1i51
PDBsum1i51
PubMed11257230
UniProtP55210|CASP7_HUMAN Caspase-7 (Gene Name=CASP7)

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