Structure of PDB 1hw2 Chain B

Receptor sequence
>1hw2B (length=222) Species: 562 (Escherichia coli) [Search protein sequence]
SPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLA
RDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRT
NISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFAS
GNPIYGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHD
QVYETVRRYGHESGEIWHRMQK
3D structure
PDB1hw2 The FadR.DNA complex. Transcriptional control of fatty acid metabolism in Escherichia coli.
ChainB
Resolution3.25 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B A33 E34 R35 R45 R49 I63 H65 G66 A27 E28 R29 R39 R43 I57 H59 G60
BS02 dna B P8 A9 T44 T46 T47 H65 P2 A3 T38 T40 T41 H59
Gene Ontology
Molecular Function
GO:0000062 fatty-acyl-CoA binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006631 fatty acid metabolic process
GO:0019217 regulation of fatty acid metabolic process
GO:0045723 positive regulation of fatty acid biosynthetic process
GO:0045892 negative regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1hw2, PDBe:1hw2, PDBj:1hw2
PDBsum1hw2
PubMed11279025
UniProtP0A8V6|FADR_ECOLI Fatty acid metabolism regulator protein (Gene Name=fadR)

[Back to BioLiP]