Structure of PDB 1hsl Chain B

Receptor sequence
>1hslB (length=238) Species: 562 (Escherichia coli) [Search protein sequence]
AIPQKIRIGTDPTYAPFESKNAQGELVGFDIDLAKELCKRINTQCTFVEN
PLDALIPSLKAKKIDAIMSSLSITEKRQQEIAFTDKLYAADSRLVVAKNS
DIQPTVASLKGKRVGVLQGTTQETFGNEHWAPKGIEIVSYQGQDNIYSDL
TAGRIDAAFQDEVAASEGFLKQPVGKDYKFGGPAVKDEKLFGVGTGMGLR
KEDNELREALNKAFAEMRADGTYEKLAKKYFDFDVYGG
3D structure
PDB1hsl Refined 1.89-A structure of the histidine-binding protein complexed with histidine and its relationship with many other active transport/chemosensory proteins.
ChainB
Resolution1.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HIS B Y14 S69 S70 L71 S72 R77 T120 T121 D161 Y14 S69 S70 L71 S72 R77 T120 T121 D161 MOAD: Kd=0.064uM
Gene Ontology
Molecular Function
GO:0016597 amino acid binding
Biological Process
GO:0006865 amino acid transport
GO:0071705 nitrogen compound transport
GO:1903810 L-histidine import across plasma membrane
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Cellular Component
External links
PDB RCSB:1hsl, PDBe:1hsl, PDBj:1hsl
PDBsum1hsl
PubMed8161536
UniProtP0AEU0|HISJ_ECOLI Histidine-binding periplasmic protein (Gene Name=hisJ)

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