Structure of PDB 1hct Chain B

Receptor sequence
>1hctB (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
MDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVS
DFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCH
RLTTVCP
3D structure
PDB1hct Solution structure of the human pp60c-src SH2 domain complexed with a phosphorylated tyrosine pentapeptide.
ChainB
ResolutionN/A
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B R175 T179 C185 H201 Y202 K203 T215 L237 R36 T40 C46 H62 Y63 K64 T76 L98
External links
PDB RCSB:1hct, PDBe:1hct, PDBj:1hct
PDBsum1hct
PubMed7532003
UniProtP12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)

[Back to BioLiP]