Structure of PDB 1hcs Chain B

Receptor sequence
>1hcsB (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
MDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVS
DFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCH
RLTTVCP
3D structure
PDB1hcs Solution structure of the human pp60c-src SH2 domain complexed with a phosphorylated tyrosine pentapeptide.
ChainB
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R175 T179 H201 Y202 K203 T215 L237 R36 T40 H62 Y63 K64 T76 L98
External links
PDB RCSB:1hcs, PDBe:1hcs, PDBj:1hcs
PDBsum1hcs
PubMed7532003
UniProtP12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)

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