Structure of PDB 1h9u Chain B

Receptor sequence
>1h9uB (length=201) Species: 9606 (Homo sapiens) [Search protein sequence]
MPVDRILEAELAVPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVIL
LRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVL
TELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASL
ETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTF
L
3D structure
PDB1h9u The Structural Basis for the Specificity of Retinoid-X Receptor-Selective Agonists: New Insights Into the Role of Helix H12
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LG2 B I339 A342 A343 L380 F384 R387 L397 A398 I416 C503 I18 A21 A22 L59 F63 R66 L76 A77 I95 C182 BindingDB: Ki=75nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003707 nuclear steroid receptor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1h9u, PDBe:1h9u, PDBj:1h9u
PDBsum1h9u
PubMed11782480
UniProtP28702|RXRB_HUMAN Retinoic acid receptor RXR-beta (Gene Name=RXRB)

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