Structure of PDB 1h8a Chain B

Receptor sequence
>1h8aB (length=67) Species: 9606 (Homo sapiens) [Search protein sequence]
DKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKV
EQLSRELSTLRNLFKQL
3D structure
PDB1h8a Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter
ChainB
Resolution2.23 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B A284 V285 K287 S288 R289 A17 V18 K20 S21 R22 PDBbind-CN: Kd=25.4nM
BS02 dna B K269 Y274 R278 N282 R289 K2 Y7 R11 N15 R22 PDBbind-CN: Kd=25.4nM
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:1h8a, PDBe:1h8a, PDBj:1h8a
PDBsum1h8a
PubMed11792321
UniProtP17676|CEBPB_HUMAN CCAAT/enhancer-binding protein beta (Gene Name=CEBPB)

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