Structure of PDB 1gzr Chain B

Receptor sequence

>1gzrB (length=61) Species: 9606 (Homo sapiens)

ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSPQTGIVDECCFRSCDLR
RLEMYCAPLKP

3D structure

• PDB: 1gzr Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
• Chain: B
• Resolution: 2.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	C15	B	F25 N26	F23 N24

Gene Ontology

Molecular Function

• GO:0005179 hormone activity
• GO:0008083 growth factor activity

Cellular Component

• GO:0005576 extracellular region
• GO:0005615 extracellular space

External links

• PDB: RCSB:1gzr, PDBe:1gzr, PDBj:1gzr
• PDBsum: 1gzr
• PubMed: 12135360
• UniProt: P05019|IGF1_HUMAN Insulin-like growth factor I (Gene Name=IGF1)