Structure of PDB 1gxz Chain B

Receptor sequence
>1gxzB (length=223) Species: 10116 (Rattus norvegicus) [Search protein sequence]
PLMLDTAPNAFDDQYEGCVNKMEEKAPLLLQEDFNMNAKLKVAWEEAKKR
WNNIKPSRSYPKGFNDFHGTALVAYTGSIAVDFNRAVREFKENPGQFHYK
AFHYYLTRALQLLSNGDCHSVYRGTKTRFHYTGAGSVRFGQFTSSSLSKK
VAQSQEFFSDHGTLFIIKTCLGVYIKEFSFRPDQEEVLIPGYEVYQKVRT
QGYNEIFLDSPKRKKSNYNCLYS
3D structure
PDB1gxz Structure of the Ecto-Adp-Ribosyl Transferase Art2.2 From Rat
ChainB
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S147 E159 R184 E189
Catalytic site (residue number reindexed from 1) S144 E156 R181 E186
Enzyme Commision number 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
3.2.2.5: NAD(+) glycohydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BRT B R126 G127 S147 S148 F160 Q187 R123 G124 S144 S145 F157 Q184
Gene Ontology
Molecular Function
GO:0106274 NAD+-protein-arginine ADP-ribosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:1gxz, PDBe:1gxz, PDBj:1gxz
PDBsum1gxz
PubMed12270706
UniProtP20974|NAR2B_RAT T-cell ecto-ADP-ribosyltransferase 2 (Gene Name=Art2b)

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