Structure of PDB 1gux Chain B

Receptor sequence
>1guxB (length=141) Species: 9606 (Homo sapiens) [Search protein sequence]
TSLSLFYKKVYRLAYLRLNTLCERLLSEHPELEHIIWTLFQHTLQNEYEL
MRDRHLDQIMMCSMYGICKVKNIDLKFKIIVTAYKDLPHAVQETFKRVLI
KEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHI
3D structure
PDB1gux Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7.
ChainB
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y709 K713 K720 F721 K722 I753 Y756 N757 M761 Y65 K69 K76 F77 K78 I109 Y112 N113 M117
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:1gux, PDBe:1gux, PDBj:1gux
PDBsum1gux
PubMed9495340
UniProtP06400|RB_HUMAN Retinoblastoma-associated protein (Gene Name=RB1)

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