Structure of PDB 1gqt Chain B

Receptor sequence

>1gqtB (length=307) Species: 83333 (Escherichia coli K-12)

QNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKGANQAVAA
GRSGANIAFIACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALIF
VNGEGENVIGIHAGANAALSPALVEAQRERIANASALLMQLESPLESVMA
AAKIAHQNKTIVALNPAPARELPDELLALVDIITPNETEAEKLTGIRVEN
DEDAAKAAQVLHEKGIRTVLITLGSRGVWASVNGEGQRVPGFRVQAVDTI
AAGDTFNGALITALLEEKPLPEAIRFAHAAAAIAVTRKGAQPSVPWREEI
DAFLDRQ

3D structure

• PDB: 1gqt Activation of Ribokinase by Monovalent Cations.
• Chain: B
• Resolution: 2.34 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): A252 A253 G254 D255
• Catalytic site (residue number reindexed from 1): A251 A252 G253 D254
• Enzyme Commision number: 2.7.1.15: ribokinase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CS	B	D249 I251 A285 R288 S294	D248 I250 A284 R287 S293
BS02	ACP	B	N187 T223 G225 S226 A253 G254 H279 A282	N186 T222 G224 S225 A252 G253 H278 A281
BS03	RIB	B	N14 D16 G42 N46 E143 D255	N13 D15 G41 N45 E142 D254

Gene Ontology

Molecular Function

• GO:0004747 ribokinase activity
• GO:0005524 ATP binding
• GO:0016301 kinase activity
• GO:0042803 protein homodimerization activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006014 D-ribose metabolic process
• GO:0016310 phosphorylation
• GO:0019303 D-ribose catabolic process
• GO:0046835 carbohydrate phosphorylation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:1gqt, PDBe:1gqt, PDBj:1gqt
• PDBsum: 1gqt
• PubMed: 11786021
• UniProt: P0A9J6|RBSK_ECOLI Ribokinase (Gene Name=rbsK)