Structure of PDB 1gmo Chain B

Receptor sequence
>1gmoB (length=172) Species: 9606 (Homo sapiens) [Search protein sequence]
NTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCADRCTRNKGLPFTCKA
FVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSY
KGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGG
PWCFTSNPEVRYEVCDIPQCSE
3D structure
PDB1gmo Crystal Structures of Nk1-Heparin Complexes Reveal the Basis for Nk1 Activity and Enable Engineering of Potent Agonists of the met Receptor
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IDS B R168 K170 R132 K134
BS02 SGN B Y167 K170 R181 G182 Y131 K134 R145 G146
BS03 SGN B K60 T61 K63 K24 T25 K27
BS04 SGN B R73 K78 G79 R37 K42 G43
BS05 IDS B K62 R73 K26 R37
BS06 SO4 B R126 I129 I130 G133 S135 R90 I93 I94 G97 S99
External links
PDB RCSB:1gmo, PDBe:1gmo, PDBj:1gmo
PDBsum1gmo
PubMed11597998
UniProtP14210|HGF_HUMAN Hepatocyte growth factor (Gene Name=HGF)

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