Structure of PDB 1g0i Chain B

Receptor sequence
>1g0iB (length=252) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence]
MKWDEIGKNIAKEIEKEILPYFGRKDKSYVVGTSPSGDETEIFDKISEDI
ALKYLKSLNVNIVSEELGVIDNSSEWTVVIDPIDGSFNFINGIPFFAFCF
GVFKNNEPYYGLTYEFLTKSFYEAYKGKGAYLNGRKIKVKDFNPNNIVIS
YYPSKKIDLEKLRNKVKRVRIFGAFGLEMCYVAKGTLDAVFDVRPKVRAV
DIASSYIICKEAGALITDENGDELKFDLNATDRLNIIVANSKEMLDIILD
LL
3D structure
PDB1g0i Crystal structure and catalytic mechanism of the MJ0109 gene product: a bifunctional enzyme with inositol monophosphatase and fructose 1,6-bisphosphatase activities.
ChainB
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E365 D381 I383 D384 S386 D501
Catalytic site (residue number reindexed from 1) E65 D81 I83 D84 S86 D201
Enzyme Commision number 3.1.3.11: fructose-bisphosphatase.
3.1.3.25: inositol-phosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B E365 D381 I383 E65 D81 I83
BS02 MN B D381 D384 D501 D81 D84 D201
BS03 MN B D338 E365 R498 D38 E65 R198
BS04 PO4 B E365 D381 I383 G385 S386 R498 E65 D81 I83 G85 S86 R198
BS05 INS B R468 R470 R168 R170
Gene Ontology
Molecular Function
GO:0008934 inositol monophosphate 1-phosphatase activity
GO:0016787 hydrolase activity
GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity
GO:0046872 metal ion binding
GO:0052832 inositol monophosphate 3-phosphatase activity
GO:0052833 inositol monophosphate 4-phosphatase activity
GO:0052834 inositol monophosphate phosphatase activity
Biological Process
GO:0006020 inositol metabolic process
GO:0007165 signal transduction
GO:0046854 phosphatidylinositol phosphate biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1g0i, PDBe:1g0i, PDBj:1g0i
PDBsum1g0i
PubMed11170378
UniProtQ57573|BSUHB_METJA Fructose-1,6-bisphosphatase/inositol-1-monophosphatase (Gene Name=suhB)

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