Structure of PDB 1fyr Chain B

Receptor sequence
>1fyrB (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGND
VQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
3D structure
PDB1fyr Dimer formation through domain swapping in the crystal structure of the Grb2-SH2-Ac-pYVNV complex.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R67 R86 S88 S90 S96 Q106 H107 F108 K109 L120 W121 R13 R32 S34 S36 S42 Q52 H53 F54 K55 L66 W67
External links
PDB RCSB:1fyr, PDBe:1fyr, PDBj:1fyr
PDBsum1fyr
PubMed11063574
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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