Structure of PDB 1fje Chain B

Receptor sequence
>1fjeB (length=175) Species: 10036 (Mesocricetus auratus) [Search protein sequence]
GSHMVEGSESTTPFNLFIGNLNPNKSVAELKVAISELFAKNDLAVVDVRT
GTNRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGRDSKKVRAAR
TLLAKNLSFNITEDELKEVFEDALEIRLVSQDGKSKGIAYIEFKSEADAE
KNLEEKQGAEIDGRSVSLYYTGEKG
3D structure
PDB1fje Molecular basis of sequence-specific recognition of pre-ribosomal RNA by nucleolin.
ChainB
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna B F17 V27 R49 T52 R54 F56 Y58 K89 G90 S93 K94 K95 L103 K105 R127 L128 V129 I138 Y140 F17 V27 R49 T52 R54 F56 Y58 K89 G90 S93 K94 K95 L103 K105 R127 L128 V129 I138 Y140 PDBbind-CN: Kd=2nM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:1fje, PDBe:1fje, PDBj:1fje
PDBsum1fje
PubMed11118222
UniProtP08199|NUCL_MESAU Nucleolin (Gene Name=NCL)

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