Structure of PDB 1fiq Chain B

Receptor sequence
>1fiqB (length=305) Species: 9913 (Bos taurus) [Search protein sequence]
PKQLRFEGERVTWIQASTLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNQ
LFPMIICPAWIPELNAVEHGPEGISFGAACALSSVEKTLLEAVAKLPTQK
TEVFRGVLEQLRWFAGKQVKSVASLGGNIITASPISDLNPVFMASGTKLT
IVSRGTRRTVPMDHTFFPSYRKTLLGPEEILLSIEIPYSREDEFFSAFKQ
ASRREDDIAKVTCGMRVLFQPGSMQVKELALCYGGMADRTISALKTTQKQ
LSKFWNEKLLQDVCAGLAEELSLSPDAPGGMIEFRRTLTLSFFFKFYLTV
LKKLG
3D structure
PDB1fiq Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: structure-based mechanism of conversion.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.17.1.4: xanthine dehydrogenase.
1.17.3.2: xanthine oxidase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FAD B K256 L257 V258 V259 G260 N261 T262 E263 I264 F337 A338 V342 A346 S347 G350 N351 I353 S359 D360 L404 K33 L34 V35 V36 G37 N38 T39 E40 I41 F114 A115 V119 A123 S124 G127 N128 I130 S136 D137 L181
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity
GO:0050660 flavin adenine dinucleotide binding
GO:0071949 FAD binding

View graph for
Molecular Function
External links
PDB RCSB:1fiq, PDBe:1fiq, PDBj:1fiq
PDBsum1fiq
PubMed11005854
UniProtP80457|XDH_BOVIN Xanthine dehydrogenase/oxidase (Gene Name=XDH)

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