Structure of PDB 1f3j Chain B

Receptor sequence
>1f3jB (length=187) Species: 10090 (Mus musculus) [Search protein sequence]
ERHFVHQFKGECYFTNGTQRIRLVTRYIYNREEYLRFDSDVGEYRAVTEL
GRHSAEYYNKQYLERTRAELDTACRHNYEETEVPTSLRRLEQPNVAISLS
RTEALNHHNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLIRNGDWT
FQVLVMLEMTPHQGEVYTCHVEHPSLKSPITVEWRAQ
3D structure
PDB1f3j Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice.
ChainB
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B F11 G13 L26 Y30 Y47 Y60 Y61 Y67 T71 E74 T77 H81 N82 E84A E86 F8 G10 L23 Y27 Y44 Y57 Y58 Y62 T66 E69 T72 H76 N77 E80 E82
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1f3j, PDBe:1f3j, PDBj:1f3j
PDBsum1f3j
PubMed10894169
UniProtQ31135

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