Structure of PDB 1eyr Chain B

Receptor sequence
>1eyrB (length=221) Species: 487 (Neisseria meningitidis) [Search protein sequence]
MEKQNIAVILARQNSKGLPLKNLRKMNGISLLGHTINAAISSKCFDRIIV
STDGGLIAEEAKNFGVEVVLRPAELASDTASSISGVIHALETIGSNSGTV
TLLQPTSPLRTGAHIREAFSLFDEKIKGSVVSACPMEHHPLKTLLQINEY
APMRHLSDLEQPRQQLPQAFRPNGAIYINDTASLIANNCFFIAPTKLYIM
SHQDSIDIDTELDLQQAENIL
3D structure
PDB1eyr Structure of a sialic acid-activating synthetase, CMP-acylneuraminate synthetase in the presence and absence of CDP.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.43: N-acylneuraminate cytidylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CDP B L10 R12 K21 N22 R71 A80 P105 T106 D209 I210 D211 L10 R12 K21 N22 R71 A80 P105 T106 D207 I208 D209
Gene Ontology
Molecular Function
GO:0008781 N-acylneuraminate cytidylyltransferase activity
GO:0016779 nucleotidyltransferase activity
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:1eyr, PDBe:1eyr, PDBj:1eyr
PDBsum1eyr
PubMed11113120
UniProtP0A0Z8|NEUA_NEIME N-acylneuraminate cytidylyltransferase (Gene Name=neuA)

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