Structure of PDB 1eon Chain B

Receptor sequence
>1eonB (length=234) Species: 562 (Escherichia coli) [Search protein sequence]
SLRSDLINALYDENQKYDVCGIISAEGKIYPLGSDTKVLSTIFELFSRPI
INKIAEKHGYIVEEPKQQNHYPDFTLYKPSEPNKKIAIDIKTTYTNKIKF
TLGGYTSFIRNNTKNIVYPFDQYIAHWIIGYVYTRVSLKTYNINELNEIP
KPYKGVKVFLQDKWVIAGDLAGSGNTTNIGSIHAHYKDFVEGKGIFDSED
EFLDYWRNYERTSQLRNKYNNISEYRNWIYRGRK
3D structure
PDB1eon Inhibition of EcoRV Endonuclease by Deoxyribo-3'-S-phosphorothiolates: A High-Resolution X-ray Crystallographic Study
ChainB
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B Q68 Q69 N70 L180 S183 G184 N185 T222 S223 Q67 Q68 N69 L170 S173 G174 N175 T212 S213
BS02 dna B T37 N70 K92 T93 T94 Y95 T106 T111 S112 K119 N120 S183 T186 N188 T36 N69 K91 T92 T93 Y94 T101 T106 S107 K114 N115 S173 T176 N178
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1eon, PDBe:1eon, PDBj:1eon
PDBsum1eon
PubMed
UniProtP04390|T2E5_ECOLX Type II restriction enzyme EcoRV (Gene Name=ecoRVR)

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