Structure of PDB 1ejh Chain B

Receptor sequence
>1ejhB (length=180) Species: 10090 (Mus musculus) [Search protein sequence]
EHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQL
SSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWL
ETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGR
VYKERLGLPPKIVIGYQSHADTATKNRFVV
3D structure
PDB1ejh Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y34 H37 P38 Q40 V69 W73 E132 G139 E140 D143 Y3 H6 P7 Q9 V38 W42 E101 G108 E109 D112
BS02 M7G B W56 M101 W102 E103 R157 K162 W25 M70 W71 E72 R126 K131
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ejh, PDBe:1ejh, PDBj:1ejh
PDBsum1ejh
PubMed10394359
UniProtP63073|IF4E_MOUSE Eukaryotic translation initiation factor 4E (Gene Name=Eif4e)

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