Structure of PDB 1eh4 Chain B

Receptor sequence
>1eh4B (length=293) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence]
NVVGVHYKVGRRIGEGSFGVIFEGTNLLNNQQVAIKFEPRRSDAPQLRDE
YRTYKLLAGCTGIPNVYYFGQEGLHNVLVIDLLGPSLEDLLDLCGRKFSV
KTVAMAAKQMLARVQSIHEKSLVYRDIKPDNFLIGRPNSKNANMIYVVDF
GMVKFYRDPVTKQHIPYREKKNLSGTARYMSINTHLGREQSRRDDLEALG
HVFMYFLRGSLPWQGLKAATNKQKYERIGEKKQSTPLRELCAGFPEEFYK
YMHYARNLAFDATPDYDYLQGLFSKVLERLNTTEDENFDWNLL
3D structure
PDB1eh4 Crystal Structure of a Conformation-Selective Casein Kinase-1 Inhibitor
ChainB
Resolution2.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IC1 B I18 E20 G21 I26 K41 E55 L88 L138 V153 D154 I13 E15 G16 I21 K36 E50 L83 L133 V148 D149
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1eh4, PDBe:1eh4, PDBj:1eh4
PDBsum1eh4
PubMed10749871
UniProtP40233|CKI1_SCHPO Casein kinase I homolog 1 (Gene Name=cki1)

[Back to BioLiP]