Structure of PDB 1ee4 Chain B

Receptor sequence
>1ee4B (length=423) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
QELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLV
EFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGS
VEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTAT
WTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSD
GPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQV
VINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIP
PLVKLLEVAEDKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDL
LEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKI
FNCQQNENDKIYEKAYKIIETYF
3D structure
PDB1ee4 Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha.
ChainB
Resolution2.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B S116 W153 N157 A159 S160 G161 Q192 W195 N199 D203 W237 N241 D276 W279 S30 W67 N71 A73 S74 G75 Q106 W109 N113 D117 W151 N155 D190 W193
BS02 peptide B V327 T328 G329 W363 S366 N367 E402 W405 V241 T242 G243 W277 S280 N281 E316 W319
External links
PDB RCSB:1ee4, PDBe:1ee4, PDBj:1ee4
PDBsum1ee4
PubMed10745017
UniProtQ02821|IMA1_YEAST Importin subunit alpha (Gene Name=SRP1)

[Back to BioLiP]