Structure of PDB 1eba Chain B

Receptor sequence
>1ebaB (length=207) Species: 9606 (Homo sapiens) [Search protein sequence]
KFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQL
EDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASGAPRY
HRVIHINEVVLLDAPVGLVARLASGHVVLRWLPPPETPMTSHIRYEVDVS
AGNGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWS
EPVSLLT
3D structure
PDB1eba An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B S91 S92 F93 S82 S83 F84
BS02 peptide B F93 P149 M150 T151 S152 H153 F84 P138 M139 T140 S141 H142
Gene Ontology
Molecular Function
GO:0004896 cytokine receptor activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:1eba, PDBe:1eba, PDBj:1eba
PDBsum1eba
PubMed9808045
UniProtP19235|EPOR_HUMAN Erythropoietin receptor (Gene Name=EPOR)

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