Structure of PDB 1e0o Chain B

Receptor sequence
>1e0oB (length=197) Species: 9606 (Homo sapiens) [Search protein sequence]
NNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEF
KQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDV
VERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHLKVLK
AAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVL
3D structure
PDB1e0o Crystal Structure of Fibroblast Growth Factor Receptor Ectodomain Bound to Ligand and Heparin
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SGN B H167 V175 K176 R178 H19 V27 K28 R30
BS02 IDS B T174 K176 T26 K28
External links
PDB RCSB:1e0o, PDBe:1e0o, PDBj:1e0o
PDBsum1e0o
PubMed11069186
UniProtP21802|FGFR2_HUMAN Fibroblast growth factor receptor 2 (Gene Name=FGFR2)

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